GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs1577917 | 1 | rs10944161 | chr6:86630376 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs10944163 | chr6:86658693 | SNHG5 | chr6:86386726-86388451:- | -0.61 | -7.35 | 6.78E-11 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs10944169 | chr6:86683036 | SNHG5 | chr6:86386726-86388451:- | -0.58 | -7.1 | 2.24E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs10944170 | chr6:86685469 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs9457247 | 1 | rs10946198 | chr6:167404432 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs10946199 | chr6:167404492 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs2243480 | 1 | rs10950032 | chr7:65738591 | CCT6P1 | chr7:65216092-65228661:+ | -0.64 | -5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs15676 | 1 | rs10988125 | chr9:131572903 | ENDOG | chr9:131580779-131584954:+ | 0.24 | 5.01 | 2.46E-6 | Blood metabolite levels |
| THYM | cis | rs7849270 | 1 | rs10988214 | chr9:131883752 | CRAT | chr9:131857075-131873070:- | 0.38 | 4.61 | 1.24E-5 | Blood metabolite ratios |
| THYM | cis | rs7849270 | 1 | rs10988223 | chr9:131903021 | CRAT | chr9:131857075-131873070:- | 0.42 | 4.98 | 2.82E-6 | Blood metabolite ratios |
| THYM | cis | rs7849270 | 1 | rs10988224 | chr9:131903334 | CRAT | chr9:131857075-131873070:- | 0.38 | 4.64 | 1.12E-5 | Blood metabolite ratios |
| THYM | cis | rs7849270 | 1 | rs10988232 | chr9:131915348 | CRAT | chr9:131857075-131873070:- | 0.38 | 4.61 | 1.24E-5 | Blood metabolite ratios |
| THYM | cis | rs7301826 | 1 | rs1106369 | chr12:131300095 | STX2 | chr12:131274149-131323811:- | 0.35 | 5.89 | 5.79E-8 | Plasma plasminogen activator levels |
| THYM | cis | rs7849270 | 1 | rs1107328 | chr9:131917534 | CRAT | chr9:131857075-131873070:- | -0.47 | -5.4 | 4.92E-7 | Blood metabolite ratios |
| THYM | cis | rs7223966 | 1 | rs11079508 | chr17:61750066 | TCAM1P | chr17:61934376-61941738:+ | -0.54 | -4.41 | 2.72E-5 | Body mass index |